Score: 7.00 | Title: Brittle Culm 12 , a dual-targeting kinesin-4 protein , controls cell-cycle progression and wall properties in rice .
| Author: Zhang M Zhang B Qian Q Yu Y Li R Zhang J Liu X Zeng D Li J Zhou Y | Journal: Plant J Citation: V : 63 P : 312-28 Year: 2010 Type: MEDLINE | Literature: oryza Field: abstract Doc ID: pub20444225 Accession (PMID): 20444225 | Matching Sentences: [ Sen. 3, subscore: 2.00 ]: Here , we report the functional characterization of Brittle Culm12 ( BC12 ) , a gene encoding a kinesin-4 protein . bc12 mutants display dwarfism resulting from a significant reduction in cell number and brittleness due to an alteration in cellulose microfibril orientation and wall composition . [ Sen. 4, subscore: 1.00 ]: BC12 is expressed mainly in it issues undergoing cell division and secondary wall thickening . [ Sen. 5, subscore: 1.00 ]: In vitro biochemical analyses verified BC12 as an authentic motor protein . [ Sen. 7, subscore: 1.00 ]: Mitotic microtubule array comparison , flow cytometric analysis and expression assays of cyclin-dependent kinase ( CDK ) complexes in root-tip cells showed that cell-cycle progression is affected in bc12 mutants . [ Sen. 8, subscore: 1.00 ]: BC12 is very probably regulated by CDKA ; 3 based on yeast two-hybrid and microarray data . [ Sen. 9, subscore: 1.00 ]: Therefore , BC12 functions as a dual-targeting kinesin protein and is implicated in cell-cycle progression , cellulose microfibril deposition and wall composition in the monocot plant rice .
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