Matching Sentences: [ Sen. 7, subscore: 2.00 ]: In spite of high levels of similarity in sequence and transport properties , the cellular localization of TPKa and TPKb channels was different , with TPKa localization predominantly at the large LV and TPKb primarily in smaller PSV-type compartments . [ Sen. 9, subscore: 2.00 ]: The use of TPKa : TPKb chimeras showed that C-terminal domains are crucial for the differential targeting of TPKa and TPKb . [ Sen. 5, subscore: 1.00 ]: The Oryza sativa genome encodes two TPK isoforms ( TPKa and TPKb ) that have very similar sequences and are ubiquitously expressed . [ Sen. 8, subscore: 1.00 ]: Trafficking of TPKa was sensitive to brefeldin A , while that of TPKb was not . [ Sen. 10, subscore: 1.00 ]: Site-directed mutagenesis of C-terminal residues that were different between TPKa and TPKb identified three amino acids that are important in determining ultimate vacuolar destination .
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