Matching Sentences: [ Sen. 9, subscore: 3.00 ]: For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . This type of interference , the release from glucose-induced repression of gene expression by inhibition of oxidative phosphorylation , was previously identified for the Amy3D gene , which suggests that hexokinase-mediated sugar signaling may be coordinated with the cellular energy status . Analysis of a transgenic rice cell line harboring the GUS reporter gene under the control of the CIPK15 promoter , and transient expression assay for 3 UTR of the CIPK15 gene indicate that sugar regulation of the rice CIPK15 gene is likely mediated by 2548-bp 5-flanking region , with no additional post-transcriptional control . [ Sen. 3, subscore: 2.00 ]: Calcineurin B-like ( CBL ) interacting protein kinase 15 ( CIPK15 ) is a newly identified positive regulator which is critical to directing the O ( 2 ) deficiency signal to the sugar signaling cascade as part of Amy3D ( representative Amy3 gene ) regulation in rice . It is located upstream and probably contributes to reserve mobilization under anoxia . In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . [ Sen. 1, subscore: 1.00 ]: Calcineurin B-like ( CBL ) interacting protein kinase 15 ( CIPK15 ) is a newly identified positive regulator which is critical to directing the O ( 2 ) deficiency signal to the sugar signaling cascade as part of Amy3D ( representative Amy3 gene ) regulation in rice . It is located upstream and probably contributes to reserve mobilization under anoxia . In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . [ Sen. 4, subscore: 1.00 ]: Calcineurin B-like ( CBL ) interacting protein kinase 15 ( CIPK15 ) is a newly identified positive regulator which is critical to directing the O ( 2 ) deficiency signal to the sugar signaling cascade as part of Amy3D ( representative Amy3 gene ) regulation in rice . It is located upstream and probably contributes to reserve mobilization under anoxia . In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . This type of interference , the release from glucose-induced repression of gene expression by inhibition of oxidative phosphorylation , was previously identified for the Amy3D gene , which suggests that hexokinase-mediated sugar signaling may be coordinated with the cellular energy status . [ Sen. 5, subscore: 1.00 ]: Calcineurin B-like ( CBL ) interacting protein kinase 15 ( CIPK15 ) is a newly identified positive regulator which is critical to directing the O ( 2 ) deficiency signal to the sugar signaling cascade as part of Amy3D ( representative Amy3 gene ) regulation in rice . It is located upstream and probably contributes to reserve mobilization under anoxia . In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . This type of interference , the release from glucose-induced repression of gene expression by inhibition of oxidative phosphorylation , was previously identified for the Amy3D gene , which suggests that hexokinase-mediated sugar signaling may be coordinated with the cellular energy status . Analysis of a transgenic rice cell line harboring the GUS reporter gene under the control of the CIPK15 promoter , and transient expression assay for 3 UTR of the CIPK15 gene indicate that sugar regulation of the rice CIPK15 gene is likely mediated by 2548-bp 5-flanking region , with no additional post-transcriptional control . [ Sen. 6, subscore: 1.00 ]: It is located upstream and probably contributes to reserve mobilization under anoxia . In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . This type of interference , the release from glucose-induced repression of gene expression by inhibition of oxidative phosphorylation , was previously identified for the Amy3D gene , which suggests that hexokinase-mediated sugar signaling may be coordinated with the cellular energy status . Analysis of a transgenic rice cell line harboring the GUS reporter gene under the control of the CIPK15 promoter , and transient expression assay for 3 UTR of the CIPK15 gene indicate that sugar regulation of the rice CIPK15 gene is likely mediated by 2548-bp 5-flanking region , with no additional post-transcriptional control . [ Sen. 7, subscore: 1.00 ]: In isolated starving embryos , the temporal pattern of accumulation of CIPK15 transcripts and leaky suppression of this gene suggests that factors other than CIPK15 may also be involved in the regulation of Amy3D expression . Probing of a variety of sugars and sugar analogs has shown that hexokinase mediates the sugar regulation of CIPK15 . For example , hexokinase substrates , such as mannose , 2-deoxyglucose , and other metabolizable sugars , repressed CIPK15 expression , whereas 3-O-methylglucose and 6-deoxyglucose did not . By using glucosamine , a hexokinase inhibitor , to release glucose-dependent CIPK15 suppression , we confirmed that hexokinase mediates regulation of this gene . Chemical inhibitors of mitochondrial electron transfer , proton separation or ATP synthase also effectively abolished sugar-induced repression of CIPK15 . This type of interference , the release from glucose-induced repression of gene expression by inhibition of oxidative phosphorylation , was previously identified for the Amy3D gene , which suggests that hexokinase-mediated sugar signaling may be coordinated with the cellular energy status . Analysis of a transgenic rice cell line harboring the GUS reporter gene under the control of the CIPK15 promoter , and transient expression assay for 3 UTR of the CIPK15 gene indicate that sugar regulation of the rice CIPK15 gene is likely mediated by 2548-bp 5-flanking region , with no additional post-transcriptional control .
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